Vasopressor Responsiveness Beyond Arterial Pressure

Increasing mean arterial blood pressure in sepsis: effects on fluid balance, vasopressor load and renal function

INTRODUCTION The objective of this study was to evaluate the effects of two different mean arterial blood pressure (MAP) targets on needs for resuscitation, organ dysfunction, mitochondrial respiration and inflammatory response in a long-term model of fecal peritonitis. METHODS Twenty-four anesthetized and mechanically ventilated pigs were randomly assigned (n = 8/group) to a septic control g...

Association of arterial blood pressure and vasopressor load with septic shock mortality: a post hoc analysis of a multicenter trial

INTRODUCTION It is unclear to which level mean arterial blood pressure (MAP) should be increased during septic shock in order to improve outcome. In this study we investigated the association between MAP values of 70 mmHg or higher, vasopressor load, 28-day mortality and disease-related events in septic shock. METHODS This is a post hoc analysis of data of the control group of a multicenter t...

Effect of Islamic fasting on mean arterial pressure

Introduction: World Health Organization (WHO) introduced hypertension as an epidemic in developing countries. However, hypertension is adequately controlled in only 12.5% of patients.  The aim of this study was to evaluate the relationship between Ramadan fasting and mean arterial pressure (MAP). Methods: This clinical, observational study was carried out at Medical O.P.D of Jinnah Medical Coll...

Performance of cardiac output measurement derived from arterial pressure waveform analysis in patients requiring high-dose vasopressor therapy.

BACKGROUND Arterial pressure waveform analysis of cardiac output (APCO) without external calibration (FloTrac/Vigileo™) is critically dependent upon computation of vascular tone that has necessitated several refinements of the underlying software algorithms. We hypothesized that changes in vascular tone induced by high-dose vasopressor therapy affect the accuracy of APCO measurements independen...

Arterial Pressure